TECH OFFERS

The production of insect protein powder is currently a batch process that is labor intensive and has issues with product consistency upon scale up. This technology uses automation to upscale the edible insect (House Cricket; Acheta domesticus) protein fractionation process. This will allow for the processing of 1 ton of the cricket raw material per hour and produce 3-4 tons of the protein powder per day. It is a scalable, zero-waste process that reduces overall operation costs (taking time, labor, energy into account) by roughly 30%. It is also applicable to other insect species and can be customizable to produce insect protein products according to customers’ needs. The cricket protein powder has a higher quality, consistency and safety than other insect protein products and meet international standards for global markets. It is an alternative to meat and plant-based protein and contains naturally higher nutritional values (70% protein content, complete amino acids, BCAAs, dietary fibre, and micronutrients). High value by-products are also obtained from the main process including oil and chitin that can be used in cosmetics and supplements. Automated continuous process Specification of the technology: feed input: max. 1 ton raw material /hour output capacity: max 3-4 ton powder/day control heat treatments: max. 110 C with 2 steps component fractionation > drying > pulverization > sieving > bagging Specifications of the cricket powder Particle size: <80 Mesh Colour: Light brown Appearance: Uniformly fine powder Flavor: Mild Storage: Ambient and dry Shelf life: 19 months at 25°C Allergens: Shellfish, May contain soy Contains >70% protein, <14% fat and 4.5% carbohydrates Technology Insect farms looking to process their raw materials Cricket Powder B2B Food manufacturers Food service Sports Nutrition Health and Wellness Shown application in protein blends, shakes, pastas, noodles, snacks, bars and bakery recipes The growing world population leads to increasing protein costs making it unaffordable for many people in developing countries. Insects are seen as an inexpensive source of protein that is increasingly being approved as a food source by regulatory authorities around the world. The global edible insect market and valued at $294.9 million in 2017 and is projected to grow at a CAGR of roughly 10% till 2024, when it is estimated to reach $722.9 million with insect-based protein food and beverage products (products that use insect as a source of protein) accounting for more than 40 percent. (Persistence Market Research, 2018) Scalable process with automation suitable for mass production Reduce energy and operational costs by at least 30% with minimal loss as compared to other insect protein processes High product consistency Fully utilize all parts of the insects with minimal waste Products are of high quality and high safety standards to improve consumer perception Extended shelf life due to reduced oxygen exposure Flexible and efficent process for any insect species Edible insect protein, Automation, Sustainable Technology, Low carbon, Cricket, Insect protein fractionation Foods, Ingredients, Processes, Sustainability, Food Security

Non-communicable Diseases (NCDs) are the leading cause of death globally, responsible for 74% of deaths worldwide. It is predicted that, by 2060, total deaths of NCDs per capita will increase by 52%, while those of communicable diseases decline. However, more than half of the deaths are preventable with lifestyle adjustments. Personalised healthcare and wellness have the potential to help people live longer, healthier lives, and to reduce the burden of chronic diseases. As technology advances, drawing connections between genetic data and personal insights is becoming more  prevalent. The use of genetic data ranges from lifestyle change and intervention to disease prevention. This Thai startup offers a biointelligence platform, founded to equip health professionals with comprehensive genetic information regarding patients’ or users’ predisposition to serious disease risks, which could be prevented or detected earlier. Together with an enabler platform for personalised health and wellness journey, they are able to provide tailored solutions for improved health and wellness, starting with the use of genetic data. The technology owner is seeking partners in Singapore, such as supplement manufacturers, wellness clinics, and wellness tourism, to co-develop personalised solutions that integrate the use of genetic data to help people live longer and healthier lives. The biointelligence platform was developed by a robust R&D team comprising data analysis and health professionals, and features the following: Analysis algorithm: In-house developed ethnic-specific algorithm with leading institutes, covering various applications in the industry. DNA test kit: Professional-grade (FDA-approved) and easy-to-transport (national coverage) Mobile applications: User-friendly, actionable, and highly-personalised by both health goal and DNA profile Mass usage for preventive healthcare, especially for non-communicable diseases (NCDs) Personalised self-care based on individual health goals, such as nutrition, skin and beauty, weight control, etc. Sports performance enhancement and injury prevention (both individual and team sports) Medical tourism and wellness tourism The global personalised medicine market, which includes personalised nutrition and wellness, is expected to reach over US$5.7 trillion by 2030, growing at a CAGR of 11.6% from 2022 to 2030 (Precedence Research, 2022). The startup has estimated a serviceable addressable market of $540.4 billion within SEA. Versatile usage of personal genetic composition data for various health and wellness purposes Robust research and development capability for further development of solutions Professionally-accepted among top medical and clinical institutes DNA test, preventive healthcare, personalised health and wellness solution, personalized health and wellness solution Personal Care, Wellness & Spa, Nutrition & Health Supplements, Healthcare, Diagnostics, Life Sciences, Biotech Research Reagents & Tools, Sustainability, Sustainable Living

This cutting-edge technology is setting new benchmarks in global healthcare with its focus on precision and personalized surgical devices and porous-based implants, particularly within the domain of oral and maxillofacial procedures. One of the primary challenges in contemporary surgical treatments has been the pervasive reliance on standardized devices. Such generic solutions often lead to prolonged surgical durations and extended recovery periods. In contrast, this innovative technology offers a resounding solution by providing 3D-printed surgical devices meticulously tailored to fit individual bone anatomies. The hallmark of these devices lies in their enhanced porous design, which significantly accelerates bone ingrowth and thus curtails healing times. Drawing from extensive clinical evidence, these devices have consistently demonstrated marked improvements in surgical outcomes. The underlying prowess of this technology hinges on advanced design principles and state-of-the-art manufacturing processes. By implementing a two-scale porous-based topology optimization approach, these medical devices are engineered to ensure anatomical conformity, robust mechanical stability, and optimal biological compatibility. As a result, they not only promote accelerated bone ingrowth but also ensure the mechanical integrity and longevity of the device. Poised at the crossroads of design excellence and medical proficiency, this technology is on track to redefine global healthcare standards. At the heart of this advanced medical solution lies an array of technical features designed for the modern surgical landscape: Personalized Design: The technology employs 3D remodeling and bone segmentation to generate medical devices tailored to individual bone anatomies. This ensures a perfect fit and reduces complications arising from mismatches. Two-Scale Porous-Based Topology Optimization: A notable design feature is the use of a two-scale porous-based topology optimization, ensuring devices maintain a balance between anatomical conformity, mechanical stability, and biological compatibility. Material Excellence: The devices are manufactured from biocompatible 3D-printed Titanium alloys. This material choice assures durability while conforming seamlessly to the patient's anatomy. Enhanced Osseointegration: The devices exhibit a meticulously crafted porous architecture. This design accelerates bone ingrowth without compromising the device's mechanical strength, promoting rapid post-surgery recovery and tissue stability. Comprehensive Surgical Solutions: The suite of tools includes cutting guides for precise tumor removal and patient- specific plates for impeccable facial contouring. Automated Design System: The creation of the devices is supported by an automated design system, which is proficient in 3D remodeling, bone segmentation, and swift device design, ensuring scalability and patient-centric solutions. High Mechanical Integrity: Leveraging advanced additive manufacturing processes, the technology can virtually validate the mechanical integrity and dimensional accuracy of the printed devices, thereby ensuring their long-term reliability in clinical settings. This state-of-the-art technology holds transformative potential across a spectrum of surgical and healthcare environments, fundamentally reshaping the approach to personalized medical treatments: Oral, Maxillofacial and Dental Surgeries: At the forefront of its applications is the enhancement of oral and maxillofacial procedures. The technology aids in surgeries from mandible reconstructions and orthognathic surgeries to chin adjustments and porous-based dental implants, enabling superior patient outcomes. Tumor Removal: With specialized cutting guides, precise tumor excisions are facilitated, increasing the efficiency and accuracy of oncological treatments. Facial Contouring: The meticulously designed patient-specific plates, made from high-grade titanium alloys, deliver unparalleled results in facial contouring surgeries, granting patients improved facial symmetry and aesthetics post- operation. Orthopedic and Specialized Surgeries: This technology is versatile enough to cater to a range of intricate operations, including spinal screw drilling guides, ankle rotation devices tailored for diabetic patients, and sacral reconstructions. Complex Surgical Planning: Local hospitals, even those that might not traditionally have access to advanced equipment, can now offer more complex surgeries. The precision tools and pre-planned approach allow medical facilities to undertake challenging surgical procedures with increased confidence and predictability. The 3D printed implants and medical device industry is poised for significant growth, reflecting the burgeoning demand in healthcare and dentistry sectors. The global oral and dental services market, currently valued at $302.7 billion in 2022, is predicted to skyrocket to a staggering $497.2 billion by 2028 (Grand View Research). This robust growth is propelled by several intertwined trends: the rise of an aging society, a universal shift towards precision medicine, and heightened awareness about health and hygiene. Moreover, the increasing prevalence of dental and periodontal diseases underscores the imperative for advanced medical solutions. Technological advancements in dentistry, combined with a growing appetite for cosmetic dentistry and preventive care, have further catalyzed market expansion. Within this vast landscape, the oral and dental 3D printing segment stands out prominently, valued at $3.2 billion in 2022 and projected to nearly triple by 2027. Factors accentuating this explosive growth include the rapidity, precision, and reduced labor intensity of dental 3D printing processes. Furthermore, the Asia Pacific region is emerging as a pivotal player in this upswing, forecasted to grow at a compelling CAGR of 22.6%. This region's surge is attributed to the rising demand for digital oral and dental solutions and an uptick in dental tourism. Notably, this market potential estimation exclusively considers maxillofacial and orthognathic solutions, leaving room for even more expansive growth when considering porous dental implants, another sector with a booming forecast (7.6% CAGR between 2022-28). Leveraging the capabilities of 3D printing, this technology offers medical devices that set a new benchmark in precision and personalization. Central to its innovation is the porous-based structure of the devices, which promotes better integration with surrounding tissues and optimized healing post-surgery. This distinctive feature ensures that each device, tailored to individual anatomical needs, surpasses the general fit and functionality that traditional methods achieve. Constructed from high-grade materials like titanium alloys, these 3D printed devices not only promise durability but also the benefits of porous designs, ensuring improved patient outcomes. The blend of 3D printing and porous structure also enhances the versatility of applications, from oral surgeries to orthopedic procedures. Moreover, it democratizes access to high-quality healthcare. Medical facilities of any scale can harness this technology, broadening their service offerings and delivering unparalleled patient care. The technology's hallmark lies in its synthesis of 3D-printed precision, porous-based design, and expansive applicability, distinguishing it significantly from conventional solutions. 3D printing, additive manufacturing, personalised medicine, dental implants, implant, titanium implant, personalised implant, oral surgery, maxilofacial surgery, bone, 3D printed bones, surgical implant, precision medicine Healthcare, Medical Devices, Manufacturing, Additive Manufacturing

In precision manufacturing, the ability to maintain optimum efficiency and accuracy is of critical importance. This AI Platform addresses these challenges by utilizing proprietary self-improving AI models for Automatic Defect Classification (ADC). This innovative solution incorporates AI Equipment Automation and Root Cause Mapping and provides a comprehensive system that significantly enhances production efficiency. The system seamlessly integrates Equipment Risk Analysis into existing alert mechanisms thus reducing downtime and increasing yield. At its core, it operates as a robust AI platform, featuring a user-centric interface for Machine Learning Operations (MLOps). This promotes recipe-free inspection while maintaining compatibility with a broad range of third-party software. The technology is modular and provides smooth productization of multiple AI solutions thereby increasing the effectiveness of defect inspection and analysis, assisting in equipment error recovery, and providing insights for process optimization. The technology offers an attractive solution for manufacturers across different industries interested in increasing their production efficiency and improving product quality. The technology features AI at its core to provide multiple AI tools in a modularized form for different inspection, maintenance, and process control related tasks common in precision manufacturing industry: High precision recipe-free AI based visual defect inspection and classification. Root cause mapping for indicating errors in upstream process. Non-intrusive equipment run status monitoring and error assist using learned behaviour from UI messages and operator interventions. Equipment health monitoring and logging. Equipment insight generation for process optimization and recipe refinement. Checklist based assistance and tracking for preventive maintenance and assists. Predictive maintenance capability. Ideal collaboration partners span semiconductor manufacturers, pharmaceutical firms and other precision manufacturing industries, hardware manufacturers for the production and upgrades of the vision systems, and research institutions focusing on AI. This technology has applications  in the manufacturing operations for the following industries: MedTech Pharmaceuticals Semiconductor Electronics Automotive Precision Engineering Aerospace With the projected growth and with production schedules becoming increasingly demanding, the ability to harness the power of artificial intelligence for predictive maintenance, process optimization, and quality control is a game-changer. These tools not only enhance the overall productivity but also enable companies to maintain a competitive edge in an ever-evolving landscape.  This technology is particularly attractive to these markets due to its ability to drastically reduce scrap rates and improve OEE (Overall Equipment Efficiency), thereby leading to significant cost savings. The growing trend of automation and AI adoption in manufacturing presents a substantial market opportunity for this technology.  The unique value proposition of the AI platform lies in its increased precision, flexibility, scalability, and seamless integration into existing manufacturing ecosystems: The solution does not require a complete overhaul of the existing setup. The solution includes a full toolset for autonomous operations - standalone AI assisted inspection, preventive maintenance, modules for reducing machine downtimes and manual assists (OEE). All actions taken are fully tracked for unique insights, root cause analysis, assisted recipe creation and process optimization. Flexible and capable of integrating techniques, like hyperspectral imaging, for insights into material properties among others. Modular and capable of adapting to various operational needs spanning different industries. Cost effective and easy integration to existing manufacturing lines. Manufacturing, Assembly, Automation & Robotics

Egg white is a well-known super-food as an absolute protein with a complete essential amino acid profile, easily digestible, and no cholesterol. While salted egg yolks are a common ingredient in many traditional Asian dishes, the egg white is discarded as it has limited applications due to its high salt content. This technology valorizes the salted egg white waste from the production of salted egg yolks into a tofu-like form that has many culinary applications. This is done using a patent-pending technique that is developed for desalination and reformation of egg white protein. The process uses a thermal membrane technique to desalinate the egg white and then aggregate the egg white protein from the salted egg white sidestream. The current production volume of this product is 50 kg/day. The egg white product is 100% natural with no additives. It comes in the form of a semi-gel “tofu”. Per 100 g of tofu, it contains 54 kcal, and 307 mg of sodium with a 12.5% protein content wet weight basis. Its texture is firmer and more chewy than regular egg white. - Suitable to be incorporated into culinary applications e.g. tofu basil stir fry, grilled tofu, salad/wrap topping - Suitable for elderly, patients, fitness enthusiasts, flexitarians, health-conscious, people seeking convenience At present, the global market size of egg white protein is valued at roughly 20 billion USD. However, there is still a large amount of egg white being discarded each year, especially in the salted egg yolk industry. The estimated value of upcycling this waste stream is estimated to be valued at 170 M baht (4.7M USD) within 3 years. This product is a healthy, tasty food with natural ingredients and no food additives that is also easy and convenient to eat. Its protein content is greater than regular egg white due to the concentration by the thermal membrane technology. This product is also easy to incorporate into culinary applications with a pleasant taste. High Protein, Egg White, Tofu, Protein Recovery, Zero-Waste Foods, Ingredients, Processes, Sustainability, Food Security

Biomarkers are biomolecules and/or physical characteristics found in the body that give a clear picture of a person’s health and fitness. Currently, the golden standard of biomarker testing is through blood tests. However, this method is invasive as it involves drawing blood with a needle. Additionally, blood tests are neither real-time nor continuous which means there is significant delay between testing and receiving results. Such problems can be solved through this invention as this method involves sensing biomarkers within sweat through a skin patch, eschewing the need for needles. Furthermore, the biomarker data can be instantly transmitted to a smartphone application which allows users to continuously monitor their data in a convenient manner.  This technology would be relevant in numerous industries such as sports fitness, beauty, and medical diagnostics; thus, attracting sizable demand for it where there is an unmet need for convenient, accurate and real time detection of accurate biomarkers. The technology consists of the following main parts:  The underlying substrate of the sweat sensor is made from advanced Ultra High Molecular Weight Polyethylene (UHMWPE) membrane which can adhere to skin without needing any adhesive. The membrane itself has the Janus property which allows biomarkers of interest to enter the sensor on the skin-side while blocking interferents such as water droplets from entering on the opposite side. The sensors use selective biomolecule detection using specially molecularly imprinted polymers (MIP) that binds to a target biomarker to generate a response signal.  The transducer part converts the biomolecular signal into an electrical signal to be processed and transmitted into the smartphone application. The smartphone app interprets and shows the data to the user with the goal of delivering insights on the user’s health and fitness.  There are several potential industries where this technology can be customised:  Sports Performance Monitoring: This technology can detect changes in lactate levels in athletes. Currently, athletes regularly use invasive blood pricks to obtain insights and improve on their lactate threshold (maximum lactate concentration in blood in which the athletes will experience fatigue). With this technology, athletes can not only bypass the invasive blood pricking but also continuously monitor their lactate levels during training instead of relying on multiple point-in-time measurements that might give an incomplete picture of their fitness levels  Beauty: Another biomarker this technology can detect is changes in cortisol, a stress hormone that negatively impacts skin health. Beauty-conscious users can apply a skin patch to detect their stress levels and perhaps implement the optimal skin care routine. Medical diagnostics: Current biomarker detection methods for medical diagnostics still rely on blood testing, which is invasive and relies on delayed point-in-time measurements. Sweat sensing using this skin-adhering sensor can give continuous non-stop insights to medical providers to optimise care based on the physiological state of the patient. The global wearable health sensors market size accounted for USD 2.9 Billion in 2022 and is estimated to achieve a market size of USD 14.1 Billion by 2032, growing at a CAGR of 17.4% from 2023 to 2032. (Source: Acumen Research and Consulting). With more people becoming health-conscious, there is an escalating demand for technologies that can assist in monitoring and enhancing their health. Wearable health sensors cater to this need by offering real-time data on a range of health parameters. In recent years, significant research has been targeted toward the development of wearable sensing devices for monitoring biomarker levels in nonobtrusively accessible biofluids such as tears, urine, saliva, and sweat. Sweat could be an ideal candidate for prolonged, semicontinuous, and non-obtrusive health monitoring because sweat is a continuously accessible biofluid containing physiologically and metabolically rich information such as biomarkers.  State of the art for biomarker detection is through using blood tests. This technology is an improvement over blood tests as it is non-invasive and increases user convenience. It has advantages in delivering real-time and continuous data to users which creates a clearer picture of the user’s health and fitness, allowing for rapid action to be taken if necessary. This contrasts with blood tests which usually require a few days between blood taking and results publishing.  This technology is an improvement as it can measure relevant biomarkers providing a more insightful view of the user’s health and with modular sensing (meaning products based on this technology can be easily modified to detect different biomarkers or even detect multiple biomarkers at once). The technology serves as a platform for customisation with multiple potential use cases in numerous industries.  skin sensor, sweat sensor, non-invasive sensor, biomarker sensor, real time data, continious monitoring, wearable, skin wearable, skin patch, wearable sensor, sweat, biomarker, platform technology Electronics, Sensors & Instrumentation, Healthcare, Diagnostics, Medical Devices

Amidst the imposition of compulsory climate reporting by regulatory bodies in some nations including Singapore, a powerful carbon accounting software solution has been devised. This aims to aid and fortify companies in their readiness to adhere to this necessity and embark on their sustainability journey. The software suite consists of the following solutions: GHG Emissions Management: Efficiently manage and reduce your organisation's greenhouse gas (GHG) emissions. ESG Reporting: Streamline and simplify your Environmental, Social, and Governance (ESG) reporting process. Environmental Compliance: Propel your organisation towards comprehensive ISO 14001 environmental stewardship. 24/7 Electricity Emissions Traceability: Navigate your decarbonisation journey with real-time, precise and transparent electricity emissions tracking. GHG Emissions Management At the heart of the software suite is the GHG Emissions Management solution. An all-in-one GHG emissions management software, to streamline calculating, tracking, and reporting your organisation's greenhouse gas (GHG) emissions for Scope 1, 2, and 3 activities. Accurate & Instant Emissions Calculations Transparent Target Setting & Progress Tracking Actionable Insights for Emissions Reduction Seamless Integration & Automation Data Validation & Stakeholder Engagement Offset Your Unavoidable Emissions Simplified Reporting & Compliance ESG Reporting Navigating the complex world of ESG reporting is now easier than ever with a powerful, user-friendly solution designed to save your organisation time, reduce stress, and optimise your reporting process across multiple international frameworks. Easily share disclosure questions to individuals across your company, manage their response and get knowledge from your disclosures by turning them from a compliance burden to valuable business insight. ESG Framework Templates Hub – GRI, TCFD, CDP, SASB and more ESG Data Consolidation Portal   Customised Data Insights Suite Environmental Compliance The solution incorporates features to support you when complying with ISO14001. Store all documents in one place, identify nonconformities, and create effective action plans. Audit Management and Reporting Data Health Check and Warnings Documentation Repository Data Verification and Tracking Automated Data Collection Target Setting and Tracking Electricity Emissions Traceability A latest feature is Electricity Emissions Traceability: Get real-time, precise and transparent electricity emissions tracking telling the user the intensity of the electricity from their grid on an hourly basis.   The suite of solutions are aimed at organisations taking proactive steps to measure and report their environmental and social impacts. GHG Emissions Management: Aimed at those organisations already calculating their carbon footprint looking for a more efficient solution or consultants providing carbon accounting as a service. ESG Reporting: Is useful for organisations already struggling with the compliance burden of disclosing to a different frameworks looking for ways to increase the efficiency of the process. Environmental Compliance: A solution perfect for any organisation who is ISO14001 accredited. 24/7 Electricity Emissions Traceability: A must have for those trailblazers wanting to go that step further and set an example for more accurate scope 2 reporting to encourage carbon free energy production locally.  This software solution provides sustainability consultants and partners allowing for a well-structured solution implemented quickly for their clients. This suite of software solutions is unique in combining a powerful carbon accounting tool with ESG reporting framework support, ISO14001 compliance functionality and real time scope 2 emissions reporting. Limited software company provides this suite of solutions designed to help you collect, calculate, measure, report and disclose your ESG data.     Infocomm, Big Data, Data Analytics, Data Mining & Data Visualisation, Green ICT, Sustainability, Low Carbon Economy

In 2022, about 83 million patients suffer from insulin-dependent diabetes worldwide. From 2021 to 2045, this number is projected to increase by 46% globally. Despite the availability of approved insulin therapy as the standard of care, up to a quarter of these patients still suffer from poor blood glucose control, which can lead to a fatal drop in blood glucose levels. The team has developed a cell-encapsulating macro-device as an implant to reduce the risk of fatal drop in blood sugar of insulin-dependent diabetic patients. This patent-pending, injection-free cellular implant can effectively manage insulin-dependent diabetes by enabling enhanced survival of therapeutic insulin-secreting cells. After a simple under-skin insertion of the macro-device, the cells in this implant can sense the blood glucose level of a diabetic patient and secrete insulin to continuously provide injection-free, precise glucose control. The device also protects the insulin secreting therapeutic cells by encapsulating them in a hydrogel to shield them from immune attacks and alleviate the patient from the need for immunosuppression. This technology could offer a safer alternative treatment for these insulin-dependent patients who experience poor blood glucose control with conventional insulin therapy. This platform technology includes two main components: a protective hydrogel membrane and living therapeutic cells. These cells are encapsulated within the hydrogel, which has controllable pores. These pores are large enough for nutrients and therapeutic agents to pass through, allowing the cells to survive and function normally. Furthermore, the pore size is small enough to block the entry of immune cells and harmful molecules, protecting the therapeutic cells from the patient's immune system. This protection eliminates the need for lifelong use of immunosuppressants, easing the burden on the patient. Once implanted inside the patient, the therapeutic cells inside the device can sense the biological environment and secrete their therapeutic agents, typically insulin in the case of diabetes, as required. The proprietary device design also improves oxygen access for the therapeutic cells by arranging them in donut-shaped microtissues, providing more surface area for oxygen intake compared to their natural spheroidal shape. These microtissues are then organized into arrays to prevent aggregation, enhancing survival of the therapeutic cells and potentially prolonging treatment duration without the need for additional agents or accessories. The technology development is currently focusing on treatment for insulin-dependent diabetes. In addition to this indication, it could serve as a platform technology for the treatment of other hormone-deficiency diseases by encapsulating different types of therapeutic cells to secrete missing hormones of interest. The applicable indications include, but are not limited to, hemophilia A and thyroid disorder. With 83 million patients worldwide suffering from insulin-dependent diabetes in 2022, there is an urgent unmet need for a safer alternative treatment for patients unresponsive to insulin therapy. The proposed cellular therapy has the potential to fulfil this need, and there is no similar treatment already approved and available in the market. Targeting the young insulin-dependent patient population (Type 1 Diabetes) experiencing poor blood glucose control and able to afford the treatment, it is estimated that the service obtainable market in the United States could achieve an annual revenue of approximately 70 million USD. A similar estimation values the Chinese market at 37 million USD annually.  The  macro-device implant is designed to provide continuous and precise blood glucose control without requiring manual intervention and injection. The proprietary hydrogel design provides protection from immune rejection as alleviating the patient from the burden of lifelong immunosuppressant usage. The device design also potentially improves the survival of encapsulated cells, promising a sustainable and prolonged efficacious duration without overburdening the patient with additional accessories. diabetes, type 1 diabetes, injection free insulin delivery, insulin, insulin delivery, cell therapy, therapeutics, stem cells, hydrogel, implant, implant device Healthcare, Medical Devices, Pharmaceuticals & Therapeutics

Histopathology is a cornerstone of modern medicine, providing crucial information that enables doctors to formulate optimal treatment strategies before, during, and after surgeries. However, current methods for obtaining histological images grapple with a compromise between speed and accuracy and suffer from organ-dependent inconsistencies. Addressing these challenges, our technology was developed as a versatile solution to cater to a wide array of clinical scenarios. It sets a new benchmark for medical standards with its rapid, precise, and label-free on-the-spot imaging capability. Computation High-throughput Autofluorescence Microscopy by Pattern Illumination is a one-of-a-kind patented solution n that can detect and provide instant information about cancer status before, during, and after surgeries. This technology lets surgeons place fresh tissue samples taken directly from the patient into the microscope and receive high-resolution and virtually stained histological images in just three minutes. The primary adopters of this technology are expected to be healthcare organizations, hospitals, and research institutions, or any entity involved in histopathology, cancer diagnosis, and surgery. This technology fills a crucial void in the market by providing swift, high-resolution, label-free imaging of thick tissue samples, an achievement previously unattainable. Consequently, this technology not only accelerates the diagnostic process but also enhances its precision, revolutionizing the field of histopathology This is an innovative solution designed to revolutionize histological imaging. It consists of several key components that contribute to its functionality: Ultraviolet Light Source: The microscope uses UV light to excite the surface of the specimen, which generates autofluorescence from the biomolecules. This autofluorescence is then captured to produce a high-resolution grayscale image. Low-magnification Objective Lens: This component provides a large field of view and is insensitive to the surface roughness of the sample. Despite its low magnification, it contributes to the high imaging speed of the technology. Pattern Illumination: This technique has been incorporated to overcome the limitations of the low-magnification lens. It helps to mathematically retrieve high-frequency signals and reconstruct high-resolution images by capturing more details and contours. Deep-learning Algorithm: This deep learning algorithm is developed to virtually stain the grayscale images with over 90% accuracy, transforming them into virtually stained H&E images. This aids in the interpretation of the images by pathologists, facilitating an easier and swift adaptation of the technology. The technology holds immense potential across various sectors, predominantly in healthcare and medical research. It can be utilized during biopsy sessions preceding surgeries, providing doctors with a rapid means to verify sample sufficiency. This capability can minimize the need for repeated biopsies, thereby improving patient comfort and experience. Furthermore, it aids in preserving the integrity of the tissue sample, facilitating subsequent consumptive testing. In the operating room, this technology can serve as an intraoperative imaging tool, potentially replacing frozen sections. This enables more rapid and precise intraoperative margin analysis during various cancer resection surgeries. With its capacity for swift and accurate imaging of freshly-excised thick tissue, our technology  is anticipated to play an instrumental role in promoting conservative surgeries. Such procedures aim to preserve more normal tissues during tumor removal, enhancing patient physiological function and life expectancy without compromising treatment efficacy. Lastly, the device can function as a tool for the digitization of tissue samples post-surgery. Hospitals often retain tissue samples for up to 10 years as a reference record. However, physical storage demands significant space and resources to maintain tissue conditions. The  ability to digitize these tissues provides a more accessible and convenient resource for research institutes and doctors to conduct further studies, thereby optimizing storage and potentially expediting medical research. The market size for the technology is substantial, considering it serves the healthcare and medical research sectors, both of which are substantial and growing markets. The global histopathology services market was valued at around USD 22.68 billion in 2020 and projected to grow at a CAGR of 6.5% from 2021 to 2028, reaching approximately USD 37 billion by 2028. The market for medical imaging equipment, which the CHAMP Microscope™ would also fall under, was projected to reach USD 43.3 billion by 2027. These figures suggest a substantial potential market for the technology. This technology stands as a significant improvement over the current clinical gold standard in histopathological imaging. The traditional methods, including Formalin-fixed Paraffin-Embedded (FFPE) and frozen section analysis, are either time-consuming or lack precision.  The Unique Value Proposition (UVP) lies in the ability to significantly reduce the time required for histopathological imaging while maintaining high accuracy this technology   Speed and Accuracy:  Offer a high-resolution, label-free imaging solution that can generate high-quality images in just three minutes, a significant improvement over current histopathology methods. Thick Tissue Staining : Technology can be used with both slides and freshly-excised thick tissue, eliminating the need for labour-intensive tissue processing and chemical staining. Versatility: The technology is applicable across a wide range of clinical scenarios, making it a versatile tool for various healthcare and research institutions. Deep Learning Model : The integration of a deep learning algorithm  for virtual staining enhances the technology's appeal by minimizing the learning curve for pathologists, making the transition to this new technology smoother. Cost and Resource Efficiency: By enabling on-the-spot imaging and reducing the need for repeated biopsies and surgeries, the technology can lead to significant cost and resource savings for healthcare providers. Patient Outcomes: By facilitating real-time decision-making during surgeries, the technology can improve patient outcomes. In sum, the technology offers a faster, more accurate, and more versatile solution for histopathological imaging, significantly enhancing clinical workflow efficiency and potentially leading to better patient outcomes. This combination of speed, accuracy, and convenience sets apart from the current clinical gold standards. Healthcare, Diagnostics, Medical Devices, Telehealth, Medical Software & Imaging