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Medical simulators are currently utilized in medical education across the globe due to their remarkable resemblance to human traits. The requirement to maintain patient safety and accessibility are particularly important in the healthcare sector. As a result, simulation is used more often in general education classes and professional training programs. This technology is of a training model for vessel puncture and catheterization and can be used as substitute to a soft cadaver. This model can be used in medical education and training for procedures that require the puncture and catheterization of a neck vein and/or a peripheral blood vessel. The technology is beneficial for medical education because it decreases the risk of dangers such as a perforated carotid artery, causing a pulmonary rupture, and a perforated aorta, causing complications from puncture and catheterization, due to lack of experiences and skills of the one performing the procedure. Education on the model will increase confidence, accuracy, and understanding of users, so that they become more skilled before a real practice with a patient, thus preventing complications to occur from vessel puncture. This training model for vessel puncture and catheterization comprises of a body, a neck coupled to the body, the neck comprising a neck hollow channel and a neck skin piece covering the neck hollow channel. The material composing the skin and vessels has human body features, allowing the use of an ultrasound probe to press the vessels and distinguishability between the neck veins and arteries. Moreover, the inventive model has suitable properties allowing a trainee to insert a guide wire into a vessel in order to train guide wire insertion into a vessel correctly without causing vascular injuries such as the guide wire penetrating out of the vessel, the direction  of the guide wire in the vessel being straight and not curved, folded, or bent, whereby the direction of the guide wire in the model is monitorable by ultrasound which makes it possible to clearly see the position and orientation of the guide wire in the vessel. The primary application for this technology is in medical simulation required for medical education and training for venous catheterisation and venepunture. The model can also be used to educate about head and neck vasculature of the human body.     The design of the model to have physical characteristics and contain material with human body features which enable efficient ultrasound along with vein puncture and catheterization as if performed on a real patient is beneficial for target users such as vascular surgeons, cardiothoracic surgeons, cardiologists, clinical radiologists, and anesthesiologists. The global Medical Simulation Market size is estimated to be US$ 2.2 Bn in 2023. (Source: Transparency Market Research) The global industry is likely to be valued at US$ 14.2 Bn by 2033, expanding at a CAGR of 19.1% between 2023 and 2033. The market in Asia Pacific is anticipated to expand at a CAGR of 20.4% over the projected period of 2023-2033. The industry in the region is anticipated to grow at the fastest rate due to the rise in demand for healthcare simulation and related services. Developing economies of India and China are anticipated to account for a large share of the market in Asia Pacific, led by the increase in emphasis on medical studies and research in these countries.  Students demonstrate greater comprehension of various topics when taught in combination with simulation or pre-education. In line with this, army units and other organizations have included simulations in order to improve their training procedures. In comparison to existing commercially available models this technology consists of the following unique characteristics such as The material composing the skin and vessels has human body features, allowing the use of an ultrasound probe to press the vessels and distinguishability between the neck veins and arteries. The model allows for monitoring the direction of needle puncture and following the movement of needle and guide wire, particularly to go into the vessels.  Medical Simulator, Medical Education Model, Head and Neck Model, Venepunture, Catheterisation, Venous Catheterisation, Medical Simulation, Ultrasound guided catheterisation Healthcare, Medical Devices, Telehealth, Medical Software & Imaging

Urban pipeline systems are vital, large, long-lived, complex, largely inaccessible, and aging, fraught with deficiencies and inefficiencies that result in massive losses of water resources and energy use. Thus, they present an enormous challenge to making cities sustainable, adaptive, and carbon neutral. This pipeline condition assessment technology is pioneered by experts who have leveraged advances in research and engineering science to deliver unique and optimal performances. The technology introduced the use of Time Reversal (TR) for defect detection and condition assessment of pipelines. In fact, TR technology is reliable, cost-effective, and has a long-range capability. It possesses the unique feature of providing high resolution while being non-intrusive and non-disruptive. The TR technology can detect existing leaks, bursts, blockages, malfunctioning devices (e.g., air valve), pipe wall strength condition, and harmful transient. The software provides the following functionality: Active testing: Actively probing the system to control the resolution of localization Passive testing: To detect bursts and harmful transients Real time monitoring: To assesses system dynamics and demand patterns On-demand and automatically generated reports On demand sensor control and sensor expansion Flexible & High sampling rate This technology enables the following features: Real-time autonomous remote monitoring Reliable, low cost and long-range Provides high resolution while being non-intrusive and non-disruptive - a unique technology feature Scalable for different pipe systems in terms of size, type and pipe material This technology uses an in-house interactive software that integrates and controls an automated, distributed, cloud-based monitoring and diagnostic system, which comprises multiple high-sampling rate (>1000 samples/s) data acquisition systems, transducers, and control devices deployed at access points of the pipeline system. The installed devices perform synchronized measurements between access points with previously unattainable accuracy (microseconds) thanks to integrated GPS technologies. Data is uploaded at high rates to a cloud server via 5G connections. Therefore, this technology is able to perform diagnosis tests on demand. The data obtained is stored in the cloud and processed in real time with novel TR algorithms to evaluate the integrity of the pipeline system. Potential defects and pipe wall deterioration will be displayed graphically on a virtual map of the system. The designed diagnostic system is inherently scalable; thus, it is possible to add multiple measurement and control stations according to needs and the spatial extent of the pipeline system (e.g., the water distribution network). This TR technology is scalable and, thus, can be implemented for different pipe systems (e.g., water supply systems, sewage rising mains, building pipes, district cooling systems) and for any pipe material. Such a product is an evolution of SCADA systems for pipeline monitoring and condition assessment. The interactive software integrates the world’s first real-time, fully automated, and autonomous TR-based technology for pipeline condition assessment, enabling the timely detection of defects in the district metering system to support proactive mitigation measures. The smart urban pipeline system being developed incorporates IoT for managing pipelines, significantly reducing maintenance costs and extending the lifespan of urban systems. This technology is advantageous for utility providers, designers, and asset management companies. Its application in developing estates and building pipes opens up an additional extensive market with the potential for high returns and exponential revenue growth. The regular expansion, replacement, and rehabilitation of urban pipelines present a substantial market and potential for implementing TR technology globally. Approximately 100 km/year of pipes are being added in Hong Kong, and over 40,000 km/year of pipes in Mainland China. Worldwide, millions of kilometres of urban water infrastructure will need to be added to supply the growing city populations, expected to expand globally by 2.5 billion by 2050. The replacement and rehabilitation of aging urban pipelines that exceed their service life are common practices in all urban pipeline systems. In Hong Kong, approximately HK$23.6 billion was spent on replacing 3,000 km of aged water mains from 2000 to 2015. The number of water main bursts dropped significantly, decreasing by about 98% from over 2,500 in 2000 to less than 150 in 2015, with a simultaneous reduction in the number of leaks. While Replacement and Rehabilitation (R&R) has proven effective in reducing pipe bursts, it is undeniable that the associated costs are high. The design and management of urban pipeline systems are currently constrained by the absence of a diagnostic system for the relatively inaccessible buried pipelines. Among the existing diagnostic and defect detection systems, in-pipe technologies are the most reliable. However, recent trials in Hong Kong have revealed these technologies to be costly, disruptive, time-consuming, labour intensive, and, in some cases, inconclusive, especially for defects near junctions. Other non-intrusive methods, such as acoustic correlators and noise loggers, are low in cost, but these methods are hands-on, exhibit poor performance in localization, and incur a high rate of false alarms. With the implementation of this TR technology, pipe defects (e.g., existing leaks, blockages, malfunctioning devices, pipe wall deterioration, etc.) can be detected before any serious burst occurs. As a result, the serviceable life of urban pipelines can be extended, and the costs for emergency repairs, replacements, and rehabilitation of urban pipelines can be significantly reduced. The implementation of this technology will also ensure that newly installed R&R pipes don’t suffer the same wasteful and underperforming fate as current ones. The TR technology is reliable, low cost and long-range, and it has the unique feature of providing high resolution while being non-intrusive and non-disruptive.   Pipeline, Condition Assessment, Defect Detection, Smart City, High Resolution, Non-intrusive, Novel Technology, Internet of Thing Infocomm, Big Data, Data Analytics, Data Mining & Data Visualisation, Wireless Technology, Smart Cities, Environment, Clean Air & Water, Sensor, Network, Monitoring & Quality Control Systems, Sustainability, Sustainable Living

Delivery systems of bioactive molecules play an increasingly important role in improving human health, serving as important tools for improving the efficacy and safety of a wide range of products, including cosmetics, drugs, gene therapy vectors, and food. The technology on offer is a patented, advanced delivery system adept at transporting a wide range of bioactive molecules, making it highly valuable in both the cosmeceutical and pharmaceutical sectors. This technology is a specially modified polymer, generating a three-dimensional nanogel structure when simply dissolved in water. The resultant material encompasses both hydrophobic and hydrophilic properties, ensuring its versatility and biocompatibility. In comparison to traditional liposome methods, this technology's self-assembling property expedites product development and obviates the requirement for expensive infrastructure or specialized tools. When combined with desired ingredients in water, the technology offers enhanced encapsulation for active pharmaceutical ingredients (API) molecules, addressing common issues of diminished bioavailability and instability in various healthcare products. In the cosmeceutical realm, it proves particularly effective for delivering active ingredients, facilitating skin penetration while simultaneously enhancing skin hydration due to its unique base components. Beyond its cosmetic applications, the technology holds immense potential in the pharmaceutical sector. Its unique structural attributes make it a promising candidate for delivering mRNA and gene therapies. The technology owner is interested in co-development projects, out-licensing and IP acquisition opportunities with Singapore-based personal care, healthcare, and pharmaceutical companies. The technology is a self-assembled nanoparticle polymeric colloid system, derived from chemically altered hyaluronic-based biopolymers integrated with poly(N-isopropylacrylamide). Some features of the material include: Soft and flexible Water-soluble Biocompatible Exhibits remarkable thermodynamic stability Clinically proven non-irritation and hypoallergenic High encapsulation efficiency for API molecules Augmented skin fortification alongside effective API delivery Enhanced stability, enduring elevated temperatures and diverse pH ranges Environmentally friendly – uses a water-based system that negates the use of harmful solvents The technology can be used as an ideal delivery system for various types of molecules. Possible applications include (but not limited to): Cosmeceuticals Pharmaceuticals Biomedical including drug delivery systems, mRNA and vaccines, immunotherapy Agriculture This technology addresses two major markets – cosmetics and mRNA therapeutics. Valued at USD 262 billion (2022) and USD 40 billion (2022) respectively, with this technology’s advanced delivery capabilities, it is primed to address these sectors’ evolving needs of sustainable, efficacious, and personalised products. The synergy of these sectors offers considerable potential for tapping into their growth and harnessing the benefits of the technology. Versatile delivery system Self-assembling, water-based composition allows for eco-conscious product development Enhances penetration, stability and efficacy of bioactive molecules biopolymer, delivery system, cosmetics, pharmceuticals, vaccines, gene therapy, gel, self-assembly, drug delivery, bioactive, active pharmaceutical ingredients, biocompatible, hydrophobic, hydrophilic, efficacy Personal Care, Cosmetics & Hair, Nutrition & Health Supplements, Healthcare, Pharmaceuticals & Therapeutics, Chemicals, Polymers, Bio-based

Bovine mastitis is a common and costly inflammatory condition of the udder in dairy cows, typically caused by bacterial infection. This disease negatively impacts milk production, quality, and animal welfare. This innovative technology offers a solution in the form of a post-milking dipping film. This environmentally friendly film provides long-lasting moisturisation and effective protection against bacteria, reducing the incidence of mastitis in dairy cows. Made with safe and green chemicals, it is easy to use and has the potential to reduce bovine mastitis by up to 20%. The technology provider is actively seeking R&D collaborations to develop new applications for pets or other animals or increase product efficiency. The innovative technology combines plant-based materials with a thin film to create a softened yet highly effective barrier that is eco-friendly. This green innovation provides long-lasting protection from microorganism infection in the mammary glands of cows for up to 3 hours.   This innovative technology can be deployed in the animal husbandry industry including goat, sheep, and buffalo milk production. It can be applied in topical wound care, making it a versatile solution for a variety of needs. The technology can be marketed for both post-milking teat dip and topical wound care applications, providing a comprehensive solution for the dairy and healthcare industries. This green technology is highly efficient and attractive to the market because it is safe for animals, humans, and the environment. The technology provider has identified a 71.4 million USD service obtainable market for this technology.   Plant-based & green technology Long-lasting barrier protection with high efficiency Life Sciences, Agriculture & Aquaculture, Biotech Research Reagents & Tools

The continuous growth of the demand for primary energy, predominantly derived from fossil sources, is causing severe environmental problems. However, over two-thirds of this energy is immediately dissipated as waste heat, released into the environment without any utilisation, such as during electricity production, combustion engines, and metallurgy. Paradoxically, instead of harnessing such excess heat, additional primary energy sources are used for heating purposes in buildings. Furthermore, the waste heat might pose a high risk of overheating, resulting in frequent failure of high-powered electrical and electronic devices.  This technology addresses the issue by capturing and storing the heat in a special heat sink or battery. The stored energy can be easily transported (by land transport without pipelines) and utilised at specific locations when required. The waste heat with lower temperature can be re-used, leading to substantial savings in primary energy. When integrated into the packaging of heat-generating devices (e.g., battery chargers, power electronics, etc.), excess heat is efficiently absorbed without a significant increase in device temperature. The absorbed heat is gradually emitted into the surroundings as the device's power diminishes. Charging the package with heat can maintain the optimal working temperature during cold season, enhancing the overall performance. The ideal collaboration partners include manufacturers of thermal batteries, heating or cooling systems, and components that generate high levels of heat, such as chargers and electronic devices. Potential partners also encompass companies involved in the production of waste heat, seeking viable alternatives to supply to suitable customers. This innovative technology combines phase change material (PCM) and aluminium foam to enable efficient absorption and radiation of significant amounts of thermal energy while minimising the temperature change. The reversible process involves absorbing heat to melt the PCM and radiating the heat as the PCM solidifies. The technology exhibits the following features: The exchange of latent heat occurs within a narrow temperature interval (+/- 2°C) Aluminium foam constitutes only about 20% of the total volume, with the remaining 80% filled by PCM Aluminium foam serves a dual purpose by acting as a heat distributor for effective thermal transfer and providing mechanical properties for the component Existing PCMs compatible with aluminium foam exhibit a latent heat of 250 kJ/kg and have an adjustable phase change temperature ranging from -10°C to 70°C The component can be fabricated in any desired shape and size It can directly act as device cases or covers to absorb excess heat or maintain stable operating temperatures It can function as a charging module for thermal batteries or a heating/cooling panel for room temperature control The technology can be applied wherever efficient heat management is needed. Possible applications include (but are not limited to): Packaging for power electronic components, superchargers, and LED screens Machine housings (compressors, reactors, engines, etc.) Housings for braking systems Packaging for batteries, fuel cells, hydrogen storage materials, etc. Packaging for temperature-sensitive foods such as chocolate, biological tissues, chemicals, measuring instruments Room heating and cooling systems Heating packs for heat exchangers Electric vehicles (EV) body structures (independent heating and AC) Outdoor cooling or heating for beverages and food Smart material combination of PCM and Al foam Rapid heat transfer with a thermal conductivity of 10 W/mK High porosity and low density (about 1 kg per litre) Excellent mechanical properties Non-toxic and recyclable Materials, Composites, Energy, Thermal Power System

This innovative wearable device, integrating an actuator and a sensor, addresses a pressing issue in the field of neuromuscular disease diagnosis and management. By enabling in vivo measurements of muscular elasticity and employing machine learning models for disease severity evaluation, it offers an objective and accessible solution. The wearable conforms to the human body, facilitating quantitative assessments by correlating elastic moduli with voltage amplitude, thereby eliminating the subjectivity of traditional assessments. It significantly enhances accessibility, breaking down barriers to muscle assessment, and introduces a remote monitoring capability that allows continuous tracking of muscle health during rapid joint stretches. This technology serves medical professionals, patients with neuromuscular diseases, and rehabilitation centers by providing a reliable tool for improved diagnosis and personalized treatment plans. In summary, this wearable device represents a transformative approach to assessment of muscle-related pathophysiological conditions, offering objectivity, accessibility, and remote monitoring, ultimately enhancing the quality of care and treatment outcomes. The core components of the system include a pneumatic actuator for controlled mechanical force generation, a piezoelectric sensor to measure muscle response, and integrated machine learning models for disease severity evaluation. The system is designed to seamlessly conform to the human body, its wearability ensures patient comfort and enables a point of care continuous monitoring of muscle health, a groundbreaking advancement in the field of muscular biomechanics assessment.  This technology offers a wide array of potential applications spanning various industries. In the healthcare sector, it can help with the diagnosis and treatment of neuromuscular diseases and find use in tele-rehabilitation programs. Athletes and sports professionals can benefit from improved performance and injury prevention. This technology could help in creating customized rehabilitation equipment designed for specific patient needs and conditions, making the recovery process more effective and personalized. Routine muscle health assessments can be realized, promoting proactive healthcare management across the board. The booming wearable market and recent advances in material science has led to the rapid development of the various wearable sensors, actuators, and devices that can be worn, embedded in fabric, accessorized, or tattooed directly onto the skin. Wearable actuators, a subcategory of wearable technology, have attracted enormous interest and many wearable actuators and devices have been developed in the past few decades to assist and improve people’s everyday lives. In addition, The global diagnostic wearable medical devices market size is estimated to grow by USD 7,333.3 million at a CAGR of 15.2% between 2022 and 2027. (Source: Technavio). The system provides a substantial improvement over the current state-of-the-art in muscular biomechanics assessment. Unlike existing methods that are either subjective and qualitative or hindered by bulky, stationary instruments, this system introduces a precise, objective, and patient-friendly solution. Its wearability, facilitated by a soft textile-based cuff, enables point-of-care assessments and home-based monitoring, dramatically enhancing accessibility and convenience. Furthermore, with dynamic movement analysis it can providing valuable insights into muscle behaviour during real-world activities, a dimension largely unexplored by current techniques. These position the system as a transformative technology, poised to revolutionize the diagnosis and management of neuromuscular diseases and expand the horizons of muscular biomechanics assessment.  soft robotics, sensor, wearable, soft actuator, muscle, muscle assessment, neuromuscular assessment, biomechanics, neuromuscular diseases, actuator, wearable sensor, skin sensor Electronics, Sensors & Instrumentation, Actuators, Healthcare, Diagnostics, Medical Devices

When developing new texture-modified products, the R&D process in achieving the desired texture is often time-consuming and expensive. Companies may also face limitations due to the minimum order quantities of individual ingredients required, as well as challenges in protecting formulation leaks from OEMs. To address these concerns faced by the industry, a Thai startup has developed a range of ready-to-use texture-modified premixes that can be directly incorporated into different food and beverage products to alter their textures. Additionally, they can provide customisation services to develop unique formulations that perfectly match the desired textures and nutrition profile for specific needs. The startup is open to collaborate with different organisations, including food manufacturers, food additive suppliers, OEMs and R&D laboratories, to create customised products. Innovation through Ingredients: Harness the power of food hydrocolloids and enzymes, known for their texture-modifying properties. Tailored Innovation: Customisation to design formulations that not only precisely match products’ texture needs, but also deliver optimal sensory experience and nutritional value, enabling businesses to craft distinctive, market-leading products. Process Optimisation: Establishing right temperature, pH and ionic strength  Ready-to-Use Texture-Modified Premixes: Reduce R&D time and costs, ensuring businesses achieve their desired product textures effortlessly. Confidentiality Assurance: Usage of premixes can protect secret recipes and mitigate the risk of formula leaks, safeguarding businesses’ intellectual property. The startup offers an extensive range of formulations that cater to diverse applications, making their solutions adaptable to a broad spectrum of food and beverage products. They are specially formulated to alter the texture of normal foods and beverages. In addition, these premixes can also modify the texture of foods and beverages for specific purposes such as making them suitable for individuals with specific dietary needs or swallowing difficulties. The startup’s unique value proposition is centered around solving several key pain points in the food and beverage industry. By simplifying and streamlining the process of achieving the desired texture in food and beverage products, providing customisation options, ensuring confidentiality, and offering a wide range of formulations to cater to various industry needs, the startup can potentially save businesses time and resources while helping them create unique and competitive products in the market. The startup is also committed to continuous research and development for new premix formulations to ensure that they stay at the forefront of texture modification technology, offering cutting-edge solutions to their clients. texture-modified premix, gelling agent, food hydrocolloids, nutrition Foods, Ingredients, Processes

Arm and hand impairment is the major problem usually found in stroke patients, which extremely affects their quality of life. Moreover, motor rehabilitation using conventional physical therapy is ineffective in stroke patients who have severe to moderate arm and hand impairment due to inability to perform voluntary movement. In order to help these patients regain arm and hand function, we have researched and developed brain-computer interface system for motor rehabilitation in stroke patients. This system can help stroke patients learn how to do voluntary arm and hand movement by using only their thoughts or brain signals; additionally, it can also enhance neural plasticity that is the key concept in stroke recovery. Finally, we aim to distribute this technology to the department of rehabilitation in hospitals, rehabilitation clinics, and home use. The technology consists of three subsystems including, Electroencephalograph (EEG) Acquisition Device Neuromuscular Electrical Stimulation (NMES) Device Motor Imagery Classification & Action Observation Module All subsystems work synchronously, from displaying the movement video, measuring brain activity while patient imagines, detecting imagination events from brain signal, and stimulating targeted muscles to create real movement. Neurorehabilitation (Stroke Rehabilitation, Spinal Cord Injury Rehabilitation, etc.) Sports Science (Mind-Body Communication Improvement) Gamification (Game control by brain signal) Insurance Provider The technology expands rehabilitation capabilities to all severity, all phases of stroke condition with its active-assisted rehabilitation method. The system is developed based on neural plasticity concept, which not only maintain, but help improves patient movement. The technology enables therapist to visualize the brain activities along with the ongoing rehabilitation process. Healthcare, Telehealth, Medical Software & Imaging

To address the challenges in chewing and swallowing faced by the elderly and other special care groups such as stroke patients, researchers from a Thai university have developed ready-to-eat wholemeal purees that serve as an all-in-one meal support. Suitable for those on an IDDSI Level 4 diet, it is designed as a healthy, special care food to provide high nutritional values and energy and to aid health rehabilitation and recovery. In addition to patients with dysphagia, this puree is also suitable for health-conscious consumers.  The team is seeking partners to bring the product to commercialisation and obtain certification according to global standards. They are also open to further develop and customise new products. Texture modification, flavour and process technologies were utilised in designing this special care food that features: Enhancement of patients’ appetite through a savoury menu with sweet flavour that also stimulates saliva to aid swallowing Safe-to-swallow, soft texture, classified as Level 4 pureed food according to International Dysphagia Diet Standardisation Initiative (IDDSI), that continues to provide patients with the feel of eating and swallowing 100% plant-based ingredients that provide high energy and nutrition High plant protein-prebiotic Cost-effective thermal process with shelf-life of 1-year at ambient temperature storage Hospital and nursing care: Suitable for swallowing practice together with nutrient and meal intake support during rehabilitation at hospital and subsequent recovery at home. Also suitable for special care groups who need softened foods with high and easily  digestible calories such as the elderly, patients after surgery, cancer patients, etc. Health and wellness: Providing holistic, nutritious meals for health support to health-conscious people who prefer plant-based and wholemeal proteins and prebiotics. Health and vegan restaurants: Incorporating this puree as a part of the menu e.g. ice-cream, breakfast bowl, etc. Baby food: Giving basic nutrients and safe-to-swallow texture for baby during the mastication practice period In 2023, the global dysphagia management market is estimated to be US$4.4 billion. It is expected to grow at a CAGR of 6.2% during the forecast period of 2023-2030. (Coherent Market Insights, 2023) Smaller serving size but higher in energy and nutrients (1 g food: 1.3-1.5 kcal) High plant protein (equivalent to 3.5-4 egg whites) No whey protein or any milk Promotes better appetite, higher food intake, faster recovery Ready-to-eat and matches with a variety of menus dysphagia, ready meal, puree, safe-swallow, IDDSI, elderly, plant-based Foods, Ingredients, Sustainability, Sustainable Living